New research presented at the European League Against Rheumatism has alarming consequences for fertility. Women with mild musculoskeletal pain were treated with three different non steroidal anti-inflammatory drugs (NSAIDS) for 10 days and then tested for ovulation. Compared to a 100% ovulation rate in the control group only 6.3% to 27.3% of the test group ovulated depending on the test drug with the drug diclofenac having the lowest rate (6.3%) and etoricoxib having the highest with just over one quarter of subjects ovulating. One of the drugs tested (naproxen) is a commonly used drug for period pain. It begs the questions how many women out there are tearing their hair out trying to fall pregnant whilst unwittingly taking these drugs and does it extend to all NSAIDS which includes over the counter medications containing ibuprofen. NSAIDS have been typically linked to erosion of the gastric lining but here we have another side effect with devastating consequences.
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